COMPOSITION AND FORM OF Tamoximed Balkan Pharmaceuticals 20 mg:
- The preparation contains tamoxifene in the form of citrate.
- 30.4 mg tamoxifen citrate is equivalent to 20 mg tamoxymede;
- Other ingredients: lactose monohydrate, corn starch, microcrystalline cellulose, magnesium stearate, silicon dioxide colloidal.
Pharmacological Properties: Pharmacodynamics. Tamoxifen is a powerful non-steroidal estrogen antagonist. It may also manifest itself as a partial or complete estrogen agonist, depending on the target tissues and species of animals under study. The anti-estrogenic effect of tamoxifene is mainly observed in humans.
The anti-estrogenic activity of tamoxifene in the human body is explained by the binding of the estrogen receptor to the hormone binding domain. Thus, tamoxifen blocks the action of estradiol.
Pharmacokinetics. When taken orally, tamoxifene is well absorbed. The maximum concentration in plasma is observed 4-7 hours after administration.
|Active ingredient, mg||20|
|1 pill, mg||20|
|Blister, pills||2, 15|
|Packing||Blister (15 pills), Packing (2 blisters)|
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