Filter products

  • Price
  • Manufacturers


Roas 10 mg Pharmacom Labs

Description Roas 10 mg Pharmacom Labs of the drug and acne treatment with it in British sport. Achi..

Add to Cart
Showing 1 to 1 of 1 (1 Pages)
Cameron Griffin
Edited By: Cameron Griffin
Updated: 04/04/2022
Status: Checked

The article is for informational purposes and is compiled according to the official instructions


Isotretinoin is a retinoid for systemic treatment of acne. Improvement of the clinical picture of severe acne is associated with suppression of sebaceous gland activity and reduction of their size, depriving Propionibacterium acnes of the main substrate for growth.

The drug inhibits the proliferation of sebocytes and acts on acne, restoring the normal process of cell differentiation.

The anti-inflammatory effect of isotretinoin on the skin has been proven.

The kinetics of isotretinoin and its metabolites are linear, it does not affect the activity of hepatic enzymes involved in drug metabolism.

In patients with acne maximum steady state plasma concentrations after fasting dose of 80 mg of isotretinoin were 310 ng/ml, reached after 2-4 hours. Plasma concentrations of isotretinoin are approximately 1.7 times higher than blood concentrations, due to poor isotretinoin penetration into erythrocytes.

Isotretinoin is 99.9% bound to plasma proteins. After oral administration, three main metabolites are detected in plasma: 4-oxo-isotretinoin, tretinoin (fully transretinoic acid) and 4-oxo-retinoin. After oral administration of radioactively labelled isotretinoin, approximately equal amounts are detected in urine and faeces. The terminal elimination half-life for the unchanged product in acne patients averages 19 hours.


Used for the treatment of severe acne (cystic nodules, conglobate acne or acne at risk of scarring) and acne unresponsive to other therapies.


  • Pregnancy
  • Breastfeeding period
  • Liver failure
  • Hypervitaminosis A
  • Severe hyperlipidaemia
  • Concomitant therapy with tetracyclines
  • Hypersensitivity to the product or its components (including soya).
  • Childhood under 12 years of age.

Side effects

  • Blood system: anaemia, neutropenia, increased erythrocyte sedimentation rate, nasal bleeding.
  • Digestive system: nausea, colitis, rarely hepatitis.
  • Musculoskeletal system: myalgia, arthralgia, rarely hyperostosis. Dermatological reactions: skin rash, dermatitis, dry mucous membranes, erythema, sweating, paronychia, nail dystrophy, increased granulation of tissues in affected areas, rarely photosensitivity, vasculitis, thinning of hair.
  • Sensory organs: photophobia, conjunctivitis, corneal clouding, decreased visual acuity at night, impaired hearing.
  • Central and peripheral nervous system: often headache, rarely depression, suicidal tendencies, seizures.
  • Allergic reactions.


As tetracyclines may cause increased intracranial pressure, their use in combination with the drug is contraindicated.

Isotretinoin may weaken the effectiveness of progesterone preparations, therefore contraceptives containing low doses of progesterone should not be used.

Combined use with topical keratolytic or exfoliative agents for the treatment of acne is contraindicated due to possible increased local irritation.

The website contains only certified products from such manufacturers:
You can buy goods from us at the best prices on the market - from 55.00€ Euro to 55.00€ Euro

The description of the active substance on this page is a simplified author's version of the site Steroidsonline-uk, created on the basis of the instructions / IU for use. Before purchasing or using the drug, you should consult a doctor and familiarize yourself with the original manufacturer's instruction (attached to each package of the drug).

Information about the preparation is provided solely with a trial purpose and should not be used as a guide to self-medication. Only a doctor may decide on the appointment of the drug, as well as determine the doses and methods of its application.

Alan Byrd

Free chat with an expert in sports pharmacology

Describe your request or specify the desired drug - we will help you choose its dosage or analogue, place an order with the delivery home or just advocate.



Online: from 9.00 to 20.00
Contact us in any way convenient for you...