Gonadotropin (human chorionic gonadotropin; hCG) is a natural hormone produced by the placenta during pregnancy, invariably excreted in the urine and processed to produce preparations. As a pharmaceutical product (lyophilizate for preparation of injections) it is widely used in traditional and sports medicine: it is used for indications ranging from menstrual disorders in women to androgenic failure in men.
Chemically, hCG (human chorionic gonadotropin) is a glycoprotein consisting of a (alpha) and b (beta) subunits: the a-subunit is identical to its analogues in TTH (thyroid hormone), FSH (follicle stimulating hormone) and LH (luteinizing hormone), while the b-subunit is unique. Structurally, it consists of a sequence of 237 amino acids, having a molecular weight of 36.7 kDa.
Gonadotropin is a multifunctional hormone in action: it has biological properties of both FSH and LH by binding to both types of gonadotropic receptors; but! its luteinizing properties are dominant - superior to those of the luteinizing hormone itself.
Effects of gonadotropin as a pharmaceutical product: for men - stimulating the synthesis of sex hormones in the testicles, sperm enhancement, improving erectile function, increased libido, the development of the genitals and secondary sexual traits; for women - stimulating the synthesis of sex hormones in the ovaries and progesterone yellow body, provoking ovulation, maintaining the development of the placenta.
Hormone gonadotropin is produced only in women, but this does not cancel its effectiveness for men. It begins to be produced in chorion tissue on ≈ 7 days after egg fertilization, being a key indicator of the presence and successful course of pregnancy. Its maximum concentration is observed at ≈ 7-11 weeks of pregnancy, after which it slowly but irreversibly decreases.
The average recommended dose of gonadotropin for athletes is 500-1500 IU per week. For a smooth background, the weekly dose is usually divided into injections on equally distant days: for example, 500 IU on Wednesday and Saturday.
The use of gonadotropin is effectively connected on a course of sports pharmacology (begin in the middle or near the end of the course and continue at least 3 weeks), not on post-course therapy (at the end of the course). The appropriateness of its use on the TCT is questionable, because by that time complications may have already formed and may not be treated with gonadotropic drugs.
It is important to understand that the injection of gonadotropin by athletes is justified precisely to prevent the development of side effects of sports pharmacology (as the suppression of sex hormone production and resulting atrophy of the testicles, oligospermia, decreased erectile function and libido), and not for their elimination post factum.
Athletes who properly carried out the use of gonadotropin, leave only positive reviews, but warn that in case of abuse, it is able to provoke side effects. Acne, increased aggression, water retention, voice coarsening, high pressure, gynecomastia and other typical testosterone disorders are likely. This is due to the specifics of the drug action.
In sport, human chorionic gonadotropin (HCG) is not used for its intended purpose, so athletes are advised to consult with a specialist in advance, receiving instructions, and examined, excluding contraindications: hypersensitivity, allergic reactions and sex hormone dependent neoplasms - in both sexes; ovarian hyperstimulation syndrome - in women; inguinal hernia, operations in the groin area and the wrong position of the testicles - in men.
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|Nome del prodotto||Prezzo|
|Preparation Pregnyl 5000 Original Organon 5000 IU||30 €|